13c-metabolic-flux
Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps,โฆ
Guided statistical analysis for research data - test selection, assumption checking, effect sizes, power analysis, Bayesian alternatives, and APA-formatted reporting. Use whenever a user wants to compare groups, test a hypothesis, analyze experimental or survey data, check
Claude Code
$ npx -y skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis --agent claude-code
Codex
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a codex -y
Cursor
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a cursor -y
Gemini CLI
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a gemini-cli -y
GitHub Copilot
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a github-copilot -y
OpenCode
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a opencode -y
Windsurf
$ npx skills add K-Dense-AI/scientific-agent-skills --skill statistical-analysis -a windsurf -y
name: statistical-analysis description: Guided statistical analysis for research data - test selection, assumption checking, effect sizes, power analysis, Bayesian alternatives, and APA-formatted reporting. Use whenever a user wants to compare groups, test a hypothesis, analyze experimental or survey data, check statistical assumptions, compute required sample sizes, or write up results - even if they never name a specific test. Covers t-tests, ANOVA, chi-square, correlation, regression, non-parametric and Bayesian methods. For low-level model APIs, see the statsmodels and pymc skills. license: MIT license compatibility: Requires Python 3.12+ and the documented isolated scientific Python environment; network access only for installation and documentation. metadata: version: "2.0" last-reviewed: "2026-10-01" skill-author: K-Dense Inc.
Conduct hypothesis tests (t-tests, ANOVA, chi-square), regression, correlation, and Bayesian analyses with systematic assumption checking, effect sizes, and APA-style reporting. Define the estimand and sampling units, diagnose model limitations, and report effect estimates with uncertainty. Numerical screens cannot certify assumptions or scientific validity.
Use this skill when:
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Targets Pingouin 0.7.0, SciPy 1.18.1, statsmodels 0.15.0, PyMC 6.3.2 and ArviZ 1.3.0 (reviewed 2026-10-01). Create a separate environment; do not add mutually incompatible scientific stacks to a shared project environment.
uv venv --python 3.12 .venv-statistics uv pip install --python .venv-statistics/bin/python "pingouin==0.7.0" "scipy==1.18.1" "statsmodels==0.15.0" pandas matplotlib seaborn # Optional Bayesian examples: uv pip install --python .venv-statistics/bin/python "pymc==6.3.2" "arviz==1.3.0"
On Windows use `.venv-statistics/Scripts/python.exe`. Lock the resolved environment for reproduction.
For model-specific APIs (OLS, GLM, ARIMA), see the **statsmodels** skill. For PyMC workflows, see the **pymc** skill.
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Use the following workflow, documenting prespecified decisions and exploratory departures.
1. **Frame the question before touching the data.** State the hypothesis, the outcome and predictor variables, and the design (independent vs. paired, number of groups). Specify the target effect, sampling unit, dependence, contrasts and multiplicity family before outcome-driven selection. Label adaptive exploration explicitly. 2. **Inspect the data.** Per group: n, mean, SD, median, missing values. Plot the raw data (histograms or box plots) before any test. Unequal group sizes, missingness, floor/ceiling effects, and outliers all change what test is appropriate โ surface them to the user rather than silently working around them. 3. **Select the test** using the quick reference below, or `references/test_selection_guide.md` for designs beyond the basics (counts, time-to-event, reliability, factorial). 4. **Check assumptions** with `scripts/assumption_checks.py`. Interpret plots and screens alongside the design and estimand; do not switch tests automatically at a diagnostic p-value threshold. Report justified sensitivity analyses and any departures from the plan. 5. **Run the test** and always compute the effect size alongside it โ a p-value assesses incompatibility with the null model; the effect estimate and its uncertainty support judgments about practical importance. 6. **Report** using the APA templates below, including descriptives, exact statistics, effect sizes with CIs, and the assumption checks performed.
If the user only needs one step (e.g., "how many participants do I need?"), jump straight to that section โ but still confirm the design assumptions the calculation rests on.
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Use `references/test_selection_guide.md` for comprehensive guidance (counts, survival, reliability, factorial designs). Quick reference:
**Group comparisons:** Independent continuous means usually use prespecified Welch's t-test or Welch's ANOVA. Pooled Student/ANOVA inference needs justified equal variance. Paired means use a paired t-test on aligned within-person differences. Repeated or clustered observations require a model of that dependence.
**Rank questions:** Mann-Whitney or Kruskal-Wallis can address distribution/rank contrasts; they are not automatic tests of medians. Wilcoxon signed-rank requires meaningful, symmetrically distributed paired differenc
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