13c-metabolic-flux
Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps,โฆ
Develops and reviews PyLabRobot lab-automation resources, liquid-handling plans, offline simulations, and supported-device integrations. Supports PyLabRobot protocols and API questions; keep physical execution behind an explicit operator safety gate.
Claude Code
$ npx -y skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot --agent claude-code
Codex
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a codex -y
Cursor
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a cursor -y
Gemini CLI
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a gemini-cli -y
GitHub Copilot
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a github-copilot -y
OpenCode
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a opencode -y
Windsurf
$ npx skills add K-Dense-AI/scientific-agent-skills --skill pylabrobot -a windsurf -y
name: pylabrobot description: Develops and reviews PyLabRobot lab-automation resources, liquid-handling plans, offline simulations, and supported-device integrations. Supports PyLabRobot protocols and API questions; keep physical execution behind an explicit operator safety gate. license: MIT compatibility: Verified against PyLabRobot 0.2.2 on Python 3.9+. Bundled planning CLIs require only Python 3.11+ and make no serial, USB, or network connections. Physical devices need model-specific extras, configuration, calibration, and trained operator approval. allowed-tools: Read Write Edit Bash metadata: version: "1.5" skill-author: "K-Dense Inc." pylabrobot-version: "0.2.2" last-reviewed: "2026-10-01"
Use PyLabRobot's hardware-agnostic frontends, resource tree, trackers, and device-specific backends to develop laboratory automation. Default to local manifest validation, bookkeeping, and the software-only chatterbox backend.
GitHub has no `v0.2.2` tag and its changelog has no 0.2.2 section. Use the released wheel/source distribution for the tested contract, not the URL label.
`EVOBackend`, `OpentronsOT2Backend`, and the software-only `LiquidHandlerChatterboxBackend`.
being listed under `Unreleased` in the current changelog. Newer development APIs, including the `track=` Hamilton deck keyword, are not this release.
hashes, tested behavior, and the known OT-2 cancellation mismatch.
Never connect to, initialize, home, move, heat, shake, spin, pump, open/close, or otherwise command physical equipment automatically. Do not turn a simulation plan into a live backend merely by changing an environment variable, config value, or import.
Before any separately authorized live run, require a trained human to:
1. Explicitly confirm the exact backend, device identity, firmware, transport, deck, and protocol revision. 2. Reconcile the physical deck against the resource tree, including carriers, adapters, lids, plates, tip racks, waste, labware orientation, barcodes, and every occupied coordinate. 3. Verify calibration, teaching, motion envelopes, collision risks, gripper or channel clearances, and all aspiration/dispense coordinates. 4. Review source identity and actual fill volume, dead volume, destination capacity, tip type/capacity/filter compatibility, channel mapping, units, heights, rates, liquid class, blowout/mixing, and contamination boundaries. 5. Confirm guards, doors, waste capacity, containment, emergency stop readiness, PPE, biosafety/chemical controls, and a safe abort/recovery procedure. 6. Approve a slow dry run or nonhazardous commissioning run when anything is new or changed.
Tracker state is **bookkeeping**, not sensing. It cannot prove that liquid or a tip is physically present. After a backend error, tracker rollback describes software state; it does not reverse a physical aspiration, dispense, or tip movement that partly completed. Preserve the error/channel details and have the operator reconcile tips and source/destination volumes before resuming. Do not blindly retry the failed operation from the pre-error plan. The [0.2.2 liquid-handler implementation](https://pypi.org/project/PyLabRobot/0.2.2/#files) commits or rolls back trackers according to reported operation success. The Visualizer renders resource/tracker events; it does not model physics. Chatterbox prints planned operations; it does not prove calibration, reachability, collision freedom, liquid behavior, or device state.
Do not guess any of these:
coordinates, orientations, and motion clearances.
mapping.
blowout, liquid properties, and validated vendor liquid class.
acceptance criteria, and recovery procedure.
If information is missing, produce an assumptions/blockers list and an offline draft only.
For offline API inspection and chatterbox simulation:
uv venv --python 3.13 .venv-pylabrobot uv pip install --python .venv-pylabrobot/bin/python "PyLabRobot==0.2.2"
On Windows, use `.venv-pylabrobot\Scripts\python.exe`. Do not install hardware extras until the user names the device and explicitly approves its transport dependencies. Then inspect the matching release source and device page before considering a pin such as `"PyLabRobot[serial]==0.2.2"` or `"PyLabRobot[usb]==0.2.2"`.
Run from the repository root. Every bundled CLI uses strict, bounded UTF-8 JSON/CSV, local non-symlink paths, fixed allowlists, and JSON output. None can select a live backend.
python3 skills/pylabrobot/scripts/validate_manifest.py \ --input tests/pylabrobot/fixtures/protocol_manifest.json python3 skills/pylabrobot/scripts/check_deck_geometry.py \ --input tests/pylabrobot/fixtures/protocol_manifest.json python3 skills/pylabrobot/scripts/plan_transfers.py \ --manifest tests/pylabrobot/fixtures/protocol_manifest.json \ --transfers tests/pylabrobot/fixtures/trans
๐ Claude Scientific Skills is now Scientific Agent Skills. Same skills, broader compatibility โ now works with any AI agent that supports the open Agent Skills standard, not just Claude.
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