13c-metabolic-flux
Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps,β¦
Builds and audits reproducible NeuroKit2 research workflows for physiological time-series preprocessing, event/interval analysis, multimodal alignment, variability, and complexity. Use when code imports neurokit2 or needs its current APIs, schemas, and method-aware
Claude Code
$ npx -y skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 --agent claude-code
Codex
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a codex -y
Cursor
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a cursor -y
Gemini CLI
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a gemini-cli -y
GitHub Copilot
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a github-copilot -y
OpenCode
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a opencode -y
Windsurf
$ npx skills add K-Dense-AI/scientific-agent-skills --skill neurokit2 -a windsurf -y
name: neurokit2 description: Builds and audits reproducible NeuroKit2 research workflows for physiological time-series preprocessing, event/interval analysis, multimodal alignment, variability, and complexity. Use when code imports neurokit2 or needs its current APIs, schemas, and method-aware validationβnot for diagnosis or device validation. license: MIT compatibility: Python 3.10+ and uv; pinned workflows use NeuroKit2 0.2.13. Core processing needs NumPy, SciPy, pandas<3, scikit-learn, matplotlib, PyWavelets, requests, and setuptools; selected EEG, cvxEDA, plotting, file-format, and RQA features need separately locked optional packages. allowed-tools: Read Write Edit Bash Glob metadata: version: "1.4" last-reviewed: "2026-10-01" skill-author: K-Dense Inc.
Use this skill for method-aware, reproducible biosignal research with NeuroKit2. The snapshot was checked on **2026-10-01** against:
`0.2.13.dev214`); and
The current wheel requires `pandas<3.0.0`. The refreshed core checks use Python 3.13, NumPy 2.5.3, and pandas 2.3.3; forcing pandas 3 conflicts with upstream metadata. API fragments below assume caller-provided arrays and imports. Optional MNE source reconstruction, cvxEDA, EMD, and pyRQA paths are source-reviewed, not runtime-validated by this refresh. Synthetic checks establish software behavior, not empirical validity.
The live documentation can be ahead of the stable wheel. Prefer the pinned runtime for reproducible work and name both versions if consulting development docs.
NeuroKit2 is a research and educational toolbox. Do **not** present its output as:
protocol, environment, population, or disease group.
Validate acquisition hardware, electrode/optode placement, units, sampling and clock accuracy, preprocessing, detector/decomposition method, population, task, and outcomes for the intended study. Preserve raw data and an auditable exclusion log. Use deidentified local files only; do not place PHI in prompts, logs, examples, or bundled fixtures.
uv pip install "neurokit2==0.2.13"
For optional features, create a uv project, add only the packages actually required at reviewed exact versions, and commit/review the resulting `uv.lock` before `uv sync --locked`. NeuroKit2 exposes an upstream `full` extra, but this skill intentionally does not install that floating transitive set in an automated workflow. Optional capabilities can require MNE, cvxopt, Plotly, PyEMD, pyRQA, Pillow, OpenCV, or file readers. Record the resolved environment with the analysis. Provision any MNE data/template download as an explicit, checksummed study input. Do not install a moving development branch for a reproducible study.
Before processing, record:
1. signal identity and sensor/channel configuration; 2. native sampling rate in Hz and physical unit (or explicitly `arbitrary_unit`); 3. clock, timestamp origin, drift correction, and synchronization evidence; 4. polarity/orientation and acquisition-side filters/gain; 5. missing samples, discontinuities, saturation, flatlines, motion, and annotations; 6. whether event onsets are zero-based sample indices or seconds; 7. planned preprocessing order, methods, parameters, exclusions, and outputs; and 8. participant-level grouping needed to prevent leakage in later statistics.
Never infer units from a column name. Do not silently treat samples as milliseconds, volts, microsiemens, or arbitrary units.
python skills/neurokit2/scripts/inspect_signal.py \ --input recording.csv --root . --deidentified \ --columns ECG,RSP,EDA --time-column time_s \ --units ECG=mV,RSP=a.u.,EDA=uS
The inspector is bounded and emits no row values or paths. Resolve non-monotonic time, duplicate samples, gaps, non-finite values, flat runs, and sampling-rate disagreement before filtering.
Use this default reasoning order, adapting it to the acquisition and cited method:
1. preserve immutable raw signal and annotations; 2. verify time base, units, polarity, clipping, gaps, and artifacts; 3. segment at long gaps; only interpolate short gaps under a declared policy; 4. apply modality-specific cleaning at the native sampling rate; 5. detect peaks/onsets or decompose components; 6. inspect quality outputs and raw overlays; 7. correct peaks only with logged categories and sensitivity checks; 8. derive rates/features; 9. align continuous modalities on a declared common time grid; and 10. map event indices to that grid, epoch, baseline, and analyze.
Do not resample binary markers or peak-index arrays as ordinary continuous signals. Map their timestamps to the target grid. Filtering and interpolation can create edge artifacts and false precision; retain masks for padded, missing, and rejected regions.
Return columns depend on NeuroKit2 version, function, method, signal availability, and analysis mode. Never claim that one column list is universal.
signals, info = nk.ecg_process(ecg, sampling_rate=250)
observed_schema = {
"columns": list(signals.columns),
"info_keys": sorted(info),
}Persist the observed schema with package version, method parameters, sampling rate, and quality/exclusion summary. Reference files list veri
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