13c-metabolic-flux
Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps,โฆ
Tracks physical units and propagates measurement uncertainty in scientific calculations using pint and uncertainties. Use for unit conversion and dimensional checking, GUM uncertainty budgets, Type A and Type B evaluation, coverage factors and expanded uncertainty, Monte Carlo
Claude Code
$ npx -y skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units --agent claude-code
Codex
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a codex -y
Cursor
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a cursor -y
Gemini CLI
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a gemini-cli -y
GitHub Copilot
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a github-copilot -y
OpenCode
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a opencode -y
Windsurf
$ npx skills add K-Dense-AI/scientific-agent-skills --skill uncertainty-and-units -a windsurf -y
name: uncertainty-and-units description: Tracks physical units and propagates measurement uncertainty in scientific calculations using pint and uncertainties. Use for unit conversion and dimensional checking, GUM uncertainty budgets, Type A and Type B evaluation, coverage factors and expanded uncertainty, Monte Carlo propagation, significant-figure and plus-minus reporting, error propagation through curve fits, CODATA constants, auditing Python code for stripped units or broken uncertainty propagation, and order-of-magnitude plausibility checks using dimensionless groups (Reynolds, Peclet, Damkohler, Knudsen, Biot, Womersley), characteristic scales such as diffusion time or Debye length, and observed magnitude ranges. Trigger on "is this number physically reasonable", "sanity check these units", "what regime is this flow in", or a result that looks off by orders of magnitude. license: MIT compatibility: Requires Python 3.12+. The numeric CLIs need pint, uncertainties, NumPy, and SciPy; the static auditor is standard-library only. All bundled tooling runs locally with no network access. allowed-tools: Read Write Edit Bash metadata: version: "1.3" last-reviewed: "2026-10-01" skill-author: K-Dense Inc.
Use this skill whenever a calculation carries physical units or a reported number needs an uncertainty. Concretely:
(wavelength to photon energy, mass to amount of substance, energy to temperature);
repeatability data;
order of magnitude, the dimensionless group, and the regime it implies.
This skill covers the metrology and the two libraries that implement it. It does not cover statistical inference, model selection, or study design โ see `statistical-analysis`, `statistical-power`, and `experimental-design`.
Verified 2026-10-01:
served CODATA 2018; the switch to CODATA 2022 occurred in SciPy 1.15.
uv venv --python 3.13 source .venv/bin/activate uv pip install "pint==0.26.1" "uncertainties==3.2.3" "numpy==2.5.3" "scipy==1.18.1"
`pint-pandas` and `pint-xarray` add unit-aware columns and arrays and are separate installs.
1. **Attach units at input and strip them only at output.** Convert at function boundaries with `ureg.wraps` or `m_as("unit")`, never mid-calculation. 2. **Write the measurement model explicitly** before computing anything, including corrections whose estimated value is zero. A correction left out of the model leaves its uncertainty out of the budget. 3. **Give every input four things**: an estimate, a standard uncertainty, the distribution the uncertainty came from, and its degrees of freedom. 4. **Convert Type B statements with the right divisor.** A certificate's expanded uncertainty divides by its stated `k`; rectangular limits divide by `sqrt(3)`. 5. **Identify correlations before combining.** A shared calibration, instrument correction, or fit can induce correlation; quantify shared components instead of assuming every pair is correlated. 6. **Compute sensitivity coefficients**, and read the budget from `c_i * u(x_i)` rather than from the raw uncertainties. 7. **Check the linearization.** Compare propagated distributions with the GUM interval when in doubt. Establish Monte Carlo numerical stability before a JCGM 101 clause 8 claim; neither method validates the measurement model or the assigned input PDFs. 8. **Justify coverage.** A Student-t factor from effective degrees of freedom is an approximation requiring suitable distributional assumptions. 9. **Round the uncertainty first, then the value to the same decimal place.** 10. **State what the `ยฑ` is** โ standard or expanded, with `k`, the coverage probability, and the method. 11. **Sanity-check the magnitude before reporting.** A dimensionally consistent result can still be impossible. Compare it against a known scale or a dimensionless group, and confirm every assumption you relied on still holds in that regime.
Each of the following runs without error and produces a plausible number.
length = (12.7 * ureg.mm).magnitude # 12.7 -- of what?
length = (12.7 * ureg.mm).m_as("m") # 0.0127 metres, stated`.magnitude` returns whatever the quantity happened to be carrying. Name the unit at the point of extraction, every time.
Q(20, "degC") + Q(5, "degC") # OffsetUnitCalculusError -- correctly refused Q(20, "degC") + Q(5, "delta_degC") # 25 degree_Celsius Q(25, "degC") - Q(20, "degC") # 5 delta_degree_Celsius
Celsius and Fahrenheit are interval scales. An uncertainty on a temperature is always a difference and belongs in a `delta_` unit: converting `20 ยฑ 0.5 degC` to Fahrenheit gives `68 degF ยฑ 0.9 delta_degF`, two different conversions on one line.
Q(10, "dBm") + Q(10, "dBm") # 0.0001 kilogram*
๐ Claude Scientific Skills is now Scientific Agent Skills. Same skills, broader compatibility โ now works with any AI agent that supports the open Agent Skills standard, not just Claude.
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