Plugin
blatant-why
AI-powered biologics design campaign agent — multi-agent orchestration with BoltzGen, PXDesign, Protenix, and 200+ cloud tools. Antibodies, nanobodies, de novo binders, and beyond.
19 skills119
@001tmfAI-powered biologics design campaign agent — multi-agent orchestration with BoltzGen, PXDesign, Protenix, and 200+ cloud tools. Antibodies, nanobodies, de novo binders, and beyond.
@001tmfBoltzGen is an all-atom diffusion model that generates antibody, nanobody, and de novo miniprotein backbones conditioned on a…
@001tmfPlan, execute, monitor, and assess protein/antibody design campaigns. This skill governs how to size a campaign, track run state,…
@001tmfMulti-round design campaigns generate scored designs at every iteration. This skill turns that scoring history into actionable…
@001tmfMost "AI scientist" demos fake reasoning by chaining LLM calls and calling the chain a hypothesis. This skill does the opposite:…
@001tmfUse the BY MCP database tools to query PDB, UniProt, and SAbDab for target characterization, antibody scaffold selection, and…
@001tmfBY is a **local-first** agent. The default compute provider is `"local"` (see `.by/config.json` → `compute.default_provider`).…
@001tmfPlan design campaigns. Analyze research, select modality, choose scaffolds, estimate costs, create campaign state, and present…
@001tmfGenerate protein/antibody designs using available compute providers (Tamarind, local GPU). Creates tool inputs, submits jobs, and…
@001tmfAnalyze sequence and structural diversity across a design set. Sequence clustering, structural clustering, Pareto front analysis,…
@001tmfDiscover available tools, compute providers, GPU access, API keys, and configuration. Produces structured environment.json for…
@001tmfDeep epitope analysis agent. Maps binding interfaces from PDB structures, classifies epitope type, assesses druggability,…
@001tmfApprove lab submission to Adaptyv Bio (triple-gated)
@001tmfFull autonomous campaign — research, design, screen, rank with minimal interruption
@001tmfLoad a protein target and analyze it for design
@001tmfPre-campaign discussion -- capture design preferences before launching
@001tmfOptional run ID (uses latest if omitted)
@001tmf© 2026 Flowy
Built for Claude Code · Not affiliated with Anthropic
Parallel epitope surface analysis. Identifies druggable sites, hotspot residues, scores epitope accessibility and druggability.…
@001tmfIndependent structural evaluation of designs. Deep structural analysis including refolding validation, interface quality,…
@001tmfFormat designs for downstream use. scFv conversion, Fab assembly, expression vector design, codon optimization hints,…
@001tmfHumanize non-human antibody sequences for therapeutic development. Framework analysis, CDR grafting onto human germlines,…
@001tmfQuery and update the learning system. Store campaign outcomes, query similar campaigns, get scaffold rankings, record failures,…
@001tmfHandle Adaptyv Bio lab submissions with triple safety gate. Presents cost estimates, validates approval chain, and submits only…
@001tmfActively propose mutations to fix identified sequence liabilities. Score mutations for structural impact, consider framework vs…
@001tmfResume an interrupted campaign from the last checkpoint
@001tmfThe design identifier or sequence to screen
@001tmfSwitch model profile (quality/balanced/budget)
@001tmfDiscover and configure compute environment
@001tmfView a protein structure in ProteinView (opens tmux split pane)
@001tmf